SYFOVRE is the first FDA-approved treatment for GA. SYFOVRE has been clinically proven to slow the growth of GA lesions in 2 clinical trials.

It’s important to know that GA cannot be cured, and the damage cannot be reversed. However, slowing down lesion growth can help delay the progression of GA.

SYFOVRE is not a one-time treatment; rather, SYFOVRE is available once every 25 to 60 days depending on your retina specialist’s recommendation.

Talk to your retina specialist about which treatment schedule may be right for you.

Stay on SYFOVRE as long as your retina specialist recommends so it can continue to delay lesion growth.

SYFOVRE is an eye injection given in-office by a retina specialist who will numb your eye beforehand.

During your appointment, your retina specialist will prepare you to receive SYFOVRE by numbing your eye. They will then inject SYFOVRE. After each injection or eye exam, your vision may be impaired; do not drive or use machinery until your vision recovers.

Do not receive SYFOVRE if you:

• have an infection in or around your eye
• have active swelling in or around your eye that may include pain and redness

SYFOVRE can cause serious side effects:

• Injections like the one for SYFOVRE can cause an eye infection (endophthalmitis) or separation of layers of the retina (retinal detachment).
• Call your healthcare provider right away if you have redness of the eye, eye pain, increased discomfort, worsening eye redness, blurred or decreased vision, an increased number of small specks floating in your vision, flashes of light, or increased sensitivity to light
• Following SYFOVRE administration, patients are at risk of developing wet age-related macular degeneration (AMD). You should be monitored for signs of wet AMD and you should report any symptoms (eg, visual distortion, deterioration in vision, black spots, loss of central vision) to your healthcare provider
• SYFOVRE may cause episodes of eye inflammation. You should report any symptoms (eg, pain or discomfort, redness, swelling, or sensitivity to light, small specks floating in your vision, changes in vision) to your healthcare provider
• SYFOVRE may cause an increase in eye pressure within minutes of the injection. Your healthcare provider will monitor this after each injection

The most common side effects with SYFOVRE are:

• Eye discomfort
• Wet age-related macular degeneration
• Small specks floating in vision
• Blood in the white of the eye

These are not all possible side effects of SYFOVRE. Tell your healthcare provider about any side effect that bothers you or that does not go away.

After a SYFOVRE injection or an eye exam, your eyesight may temporarily be impaired. Do not drive or use machinery until your vision recovers.

Please plan to have a ride to and from your appointment.

It’s a good plan to read SYFOVRE materials you receive from your eye doctor. If you did not receive any materials, please visit the Getting Started on SYFOVRE page for more information.

You can also stay informed about SYFOVRE by signing up for emails here.
If you still have questions, write them down to ask your retina specialist during your appointment.

An Amsler grid is a tool you can use to help you keep track of your vision between appointments. If you notice any changes in your vision, talk to your retina specialist. Click here to download the Amsler Grid.

Your vision may be impaired after receiving a SYFOVRE injection or after an eye exam so you may want to have someone with you to drive you home.

If an injection is missed, call your retina specialist. They will determine when you should receive your next injection.