SYFOVRE® (pegcetacoplan injection)

Watch our TV commercial to get the facts

ViewHide transcript

CUT!!!!

I get it! Slow motion. Slow down geographic atrophy.

But we don’t need gimmicks. Stick to the facts.

GA, the advanced form of dry AMD, can irreversibly damage your vision.

But SYFOVRE is an FDA-approved eye injection that gives you the power to slow GA.

SYFOVRE was proven to slow GA lesion growth over 2 years with increasing effect over time.

It's the only treatment to slow GA in as few as 6 doses per year.

Don’t take SYFOVRE if you have an infection, or active swelling in or around your eye that may include pain and redness or are allergic to it.

SYFOVRE can cause severe allergic reactions.

Other serious side effects are eye infection and retinal detachments, severe inflammation of vessels in the retina which may result in severe vision loss, wet AMD, eye inflammation, and an increase in eye pressure.

Most common side effects are eye discomfort, wet AMD, small specks floating in vision, and blood in the white of the eye.

Tell your doctor right away if you have any side effects.

Act on facts to slow GA. Ask your retina specialist about SYFOVRE.

Nope! Just the facts.

With Geographic Atrophy (GA), the facts matter.

GA, the advanced form of dry age-related macular degeneration (AMD), can cause irreversible damage to your eyes until you can't read, drive, or recognize loved ones' faces.

Only SYFOVRE was proven to slow GA progression in as few as 6 doses per year.*

*Your doctor will decide how often you receive SYFOVRE (once every 25-60 days).

Learn how SYFOVRE works

Watch the video

SYFOVRE has the largest and longest studies of any FDA-approved treatment for GA with over 1200 patients

Get the results

Explore resources about SYFOVRE and GA

Download resources

Sign up for events or watch patient testimonials.

Hear real GA stories

Get up-to-date information on GA and SYFOVRE.

Join our email list

Next
What is GA?

The resources on this website are meant to be informational only and are not intended to replace medical advice. Always talk to your healthcare provider about any medical decisions, including how to manage geographic atrophy (GA) and how it affects your everyday life.

IMPORTANT SAFETY INFORMATION

What is SYFOVRE?

SYFOVRE is a prescription eye injection, used to treat geographic atrophy (GA), the dry advanced form of age-related macular degeneration (AMD).

Who should NOT receive SYFOVRE^® (pegcetacoplan injection)?

Do not receive SYFOVRE if you have an infection or active swelling in or around your eye that may include pain and redness, or are allergic to pegcetacoplan or any ingredients in SYFOVRE. SYFOVRE can cause serious allergic reactions such as trouble breathing, tongue, face, lips, or mouth swelling, rashes, and hives.

Who should NOT receive SYFOVRE^® (pegcetacoplan injection)?

Do not receive SYFOVRE if you have an infection or active swelling in or around your eye that may include pain and redness, or are allergic to pegcetacoplan or any ingredients in SYFOVRE. SYFOVRE can cause serious allergic reactions such as trouble breathing, tongue, face, lips, or mouth swelling, rashes, and hives.

SYFOVRE can cause serious side effects:

Eye infection (endophthalmitis) or separation of layers of the retina (retinal detachment)
- Call your healthcare provider right away if you have eye redness, light sensitivity, eye pain, or any change in vision including blurred, wavy/distorted vision, small specks floating in your vision, or flashing lights
Severe inflammation of vessels in the retina which may result in severe vision loss. Call your healthcare provider right away if you have eye redness, light sensitivity, eye pain, or any change in vision including blurred, wavy/distorted vision, or flashing lights
Risk of developing wet AMD. You should be monitored for signs of wet AMD and you should report if you have any change in vision including blurred, wavy/distorted vision, black spots, or loss of central vision to your healthcare provider
Episodes of eye inflammation. You should report any symptoms including eye redness, light sensitivity, eye pain, small specks floating in your vision, or any changes in vision to your healthcare provider
Increase in eye pressure within minutes of the injection. Your healthcare provider will monitor this after each injection

Before receiving SYFOVRE:

Tell your healthcare provider if any of the following applies to you:
- If you have a history of seeing flashes of light or small specks floating in your vision and notice a sudden increase of size and number of these specks
- If you have high pressure in the eye or glaucoma

Tell your healthcare provider about all of your medical conditions, including
- If you are, or think you are pregnant, breastfeeding, or are planning to have a baby, ask your doctor for advice before taking this medicine

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements

What should I avoid while receiving SYFOVRE?

After an injection or an eye exam, your eyesight may temporarily be impaired. Do not drive or use machinery until your vision recovers

What are the most common side effects of SYFOVRE?

Eye discomfort
Wet age-related macular degeneration
Small specks floating in vision
Blood in the white of the eye

These are not all the possible side effects of SYFOVRE. Tell your healthcare provider about any side effect that bothers you or does not go away.

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

What is SYFOVRE?

SYFOVRE is a prescription eye injection, used to treat GA, the dry advanced form of AMD.

Please see full Prescribing Information for more information.

IMPORTANT SAFETY INFORMATION

Who should NOT receive SYFOVRE^® (pegcetacoplan injection)?

Do not receive SYFOVRE if you have an infection or active swelling in or around your eye that may include pain and redness, or are allergic to pegcetacoplan or any ingredients in SYFOVRE. SYFOVRE can cause serious allergic reactions such as trouble breathing, tongue, face, lips, or mouth swelling, rashes, and hives.

SYFOVRE can cause serious side effects:

Eye infection (endophthalmitis) or separation of layers of the retina (retinal detachment)
- Call your healthcare provider right away if you have eye redness, light sensitivity, eye pain, or any change in vision including blurred, wavy/distorted vision, small specks floating in your vision, or flashing lights
Severe inflammation of vessels in the retina which may result in severe vision loss. Call your healthcare provider right away if you have eye redness, light sensitivity, eye pain, or any change in vision including blurred, wavy/distorted vision, or flashing lights
Risk of developing wet AMD. You should be monitored for signs of wet AMD and you should report if you have any change in vision including blurred, wavy/distorted vision, black spots, or loss of central vision to your healthcare provider
Episodes of eye inflammation. You should report any symptoms including eye redness, light sensitivity, eye pain, small specks floating in your vision, or any changes in vision to your healthcare provider
Increase in eye pressure within minutes of the injection. Your healthcare provider will monitor this after each injection

Before receiving SYFOVRE:

Tell your healthcare provider if any of the following applies to you:
- If you have a history of seeing flashes of light or small specks floating in your vision and notice a sudden increase of size and number of these specks
- If you have high pressure in the eye or glaucoma

Tell your healthcare provider about all of your medical conditions, including
- If you are, or think you are pregnant, breastfeeding, or are planning to have a baby, ask your doctor for advice before taking this medicine

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements

What should I avoid while receiving SYFOVRE?

After an injection or an eye exam, your eyesight may temporarily be impaired. Do not drive or use machinery until your vision recovers

What are the most common side effects of SYFOVRE?

Eye discomfort
Wet age-related macular degeneration
Small specks floating in vision
Blood in the white of the eye

These are not all the possible side effects of SYFOVRE. Tell your healthcare provider about any side effect that bothers you or does not go away.

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

What is SYFOVRE?

SYFOVRE is a prescription eye injection, used to treat GA, the dry advanced form of AMD.

Please see full Prescribing Information for more information.

Thank you for signing up to attend a Real GA Story event.

Get up-to-date information on GA and SYFOVRE.

Sign up to learn how SYFOVRE can help you slow GA.

Sign up to learn how SYFOVRE can help you slow GA.

If you already receive SYFOVRE emails, you do not need to sign up again.

All fields required.

Please select the option that best describes you: Select an option
First Name Enter your first name
Last Name Enter your last name
Email Enter your email
By selecting “I agree” below, I authorize Apellis Pharmaceuticals, Inc., its affiliates and their representatives, agents, contractors and companies working with Apellis (collectively, “Apellis”), to contact me by mail, email, telephone, and text message for marketing purposes or to otherwise provide me with information about Apellis products, services, and programs or other topics of interest; conduct data analysis; or otherwise ask me about my experience with or thoughts about such topics. I understand and agree that any information that I provide may be used by Apellis to help develop new products, services, and programs. I understand that I may revoke this authorization and choose not to receive information from Apellis by clicking the “unsubscribe” link provided in emails I receive from Apellis or by emailing Apellis at info@apellis.com. I have read and understand the Privacy Policy. I agree. You must agree before submitting.