About Geographic Atrophy (GA)

GA can cause irreversible damage to the parts of your eye responsible for central vision in as few as 2.5 years.*

* According to a study of 3,640 patients with AMD, the median time to developing central GA, after any GA diagnosis in at least one eye for a subset of 397 patients, was 2.5 years.

Use the arrows to see an example of GA lesion progression in a person over time.

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Normal Retina^†

Baseline^‡

+1 Years^‡

+3 Years^‡

Images are for illustrative purposes only. Progression of GA lesions and vision impairment due to GA may vary. SYFOVRE is proven to slow GA lesion progression. It has not been shown to stop or reverse damage to vision.

^† Image courtesy of Mohammad Rafieetary, OD, Charles Retina Institute.

^‡ Reproduced from Steffen Schmitz-Valckenberg. The Journey of “Geographic Atrophy” through Past, Present, and Future. Ophthalmologica. 2017;237:11-20. Copyright 2017 Karger Publishers, Basel, Switzerland.

Use the arrows to see how GA can affect vision over time.

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GA may progress faster than you think and can damage parts of your eye that help you read, drive, and recognize faces.

How GA lesions can permanently damage your eyes

Side view of normal eye

Your retina is made up of layers of cells that include photoreceptors that send signals to help your brain process what you’re seeing.

Retina’s role in vision

Photoreceptors are concentrated in the macula, the part in the retina which is responsible for central vision.

Where GA starts to form

GA lesions can form when part of the immune system in your eye is overactivated and mistakenly damages these retinal cells.

GA damage spreads

These lesions can grow in the macula, the central part of the retina that helps you see in detail.

GA damages central vision

As GA lesions continue to grow, they move closer to the center of the macula, causing permanent damage to your central vision.

Images for illustrative purposes only. GA lesion progression may vary.

Reproduced with permission from Ruiz-Moreno et al. Fundus autofluorescence in age-related macular degeneration. AMD Book. 2017

GA Progression Poster

Learn how GA progresses and can change your vision.

Download the poster

What is Geographic Atrophy?

GA can cause irreversible damage to the parts of your eye responsible for central vision in as few as 2.5 years.*

How GA lesions can permanently damage your eyes

GA Progression Poster

Slowing GA lesion progression can help slow the damage it causes